Bowen Yan, Ph.D.
Research Assistant Professor
Department:
MD-PHARMACOLOGY / THERAPEUTICS
Business Phone:
(352) 273-5906
Business Email:
yanbowen@ufl.edu
Research Profile
Dr. Yan researches aging or DNA-damaging related hematological defects and malignancies.
Open Researcher and Contributor ID (ORCID)
0000-0003-4730-6763
Publications
Academic Articles
2024
Overcoming ABCB1 mediated multidrug resistance in castration resistant prostate cancer.
Cell death & disease.
15(8)
[DOI] 10.1038/s41419-024-06949-3.
[PMID] 39090086.
2023
Epigenetic Mechanisms in Hematologic Aging and Premalignant Conditions.
Epigenomes.
7(4)
[DOI] 10.3390/epigenomes7040032.
[PMID] 38131904.
2021
HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis
Nucleic Acids Research.
49(17):9783-9798
[DOI] 10.1093/nar/gkab737.
[PMID] 34450641.
2020
Low-frequency TP53 hotspot mutation contributes to chemoresistance through clonal expansion in acute myeloid leukemia.
Leukemia.
34(7):1816-1827
[DOI] 10.1038/s41375-020-0710-7.
[PMID] 31988438.
2019
Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia.
Leukemia.
33(4):931-944
[DOI] 10.1038/s41375-018-0279-6.
[PMID] 30291336.
2019
HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice.
Cancer cell.
36(6):645-659.e8
[DOI] 10.1016/j.ccell.2019.10.011.
[PMID] 31786140.
2018
CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia.
Blood.
132(8):837-848
[DOI] 10.1182/blood-2017-11-814319.
[PMID] 29760161.
2017
Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
31(9):4104-4116
[DOI] 10.1096/fj.201700022R.
[PMID] 28572446.
2017
Histone deacetylase 6 regulates cytokinesis and erythrocyte enucleation through deacetylation of formin protein mDia2.
Haematologica.
102(6):984-994
[DOI] 10.3324/haematol.2016.161513.
[PMID] 28255013.
Grants
Jul 2024
ACTIVE
Developing Innovative Therapeutic Strategies to Overcome Chemotherapy Resistance in Elderly Acute Myeloid Leukemia Patients
Role: Principal Investigator
Funding: OCALA ROYAL DAMES FOR CANCER RESEARCH
Jan 2022
ACTIVE
American Cancer Society Institutional Research Grant
Role: Project Manager
Funding: AMERICAN CANCER SOCIETY
Education
Ph.D.
2012
·
China Agriculture University
Contact Details
Phones:
- Business:
- (352) 273-5906
Emails:
- Business:
- yanbowen@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100267
GAINESVILLE FL 32610 - Business Street:
-
UF
GAINESVILLE FL 326100001